Author

T. M. O'Shea

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. M. Beitz· 1 shared B. A. Lende-Dorn· 1 shared E. Dubois· 1 shared H. Nia· 1 shared H. O. Adewumi· 1 shared K. E. Galloway· 1 shared L. F. Hassan· 1 shared N. B. Wang· 1 shared

Activity by Year

2023-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperCell Biology

A. M. Beitz

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Proliferation history and transcription factor levels drive direct conversion

N. B. Wang, B. A. Lende-Dorn, H. O. Adewumi, A. M. Beitz, P. Han, T. M. O'Shea, K. E. Galloway

This study identifies proliferation history and transcription factor levels as key drivers of direct conversion of fibroblasts to motor neurons using a synthetic biology approach.

bioRxiv · Nov 26, 2023 · PreprintCell Biology

Trehalose-based coacervates for local bioactive protein delivery to the central nervous system

L. F. Hassan, R. Sen, T. M. O'Shea

This study develops trehalose-based coacervates for targeted delivery of bioactive proteins to the CNS, showing high loading, controlled release, and compatibility with neural cells.

bioRxiv · Oct 5, 2023Bioengineering

Alteration of mechanical stresses in the murine brain by age and hemorrhagic stroke

S. Zheng, R. Banerji, R. LeBourdais, S. Zhang, E. Dubois, T. M. O'Shea, H. Nia

This study maps residual mechanical stresses in murine brains across age and after hemorrhagic stroke, finding increased stresses with age and reduced stresses post-stroke.

bioRxiv · Sep 25, 2023Biophysics