Author

T. P. Burghardt

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Approach:Bayesian inference· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Y. Wang· 2 shared K. Ajtai· 1 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

2 top collaborators · 1 mutual co-author link

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2 shared papersBiophysics

Y. Wang

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3 papers

Recent·Most cited

Natural variants with 2D correlation genetics identify domains coordinating sarcomere proteins during contraction

T. P. Burghardt

The paper uses 2D correlation genetics to identify co-domains in the βmys/MYBPC3 complex that coordinate sarcomere protein interactions during contraction, revealing critical regulatory sites linked to pathogenic SNVs.

bioRxiv · Mar 14, 2021 · PreprintBiochemistry

Uncured PDMS Inhibits Myosin In Vitro Motility in a Microfluidic Flow Cell

Y. Wang, T. P. Burghardt

This study investigates how PDMS inhibits myosin motility in microfluidic flow cells and identifies methods to mitigate this effect.

bioRxiv · Sep 14, 2018Biophysics

Cardiac and Skeletal Actin Substrates Uniquely Tune Cardiac Myosin Strain-Dependent Mechanics

Y. Wang, K. Ajtai, T. P. Burghardt

This study compares single myosin force-velocity on cardiac and skeletal actin substrates, finding that actin isoform stoichiometry and specific contacts influence myosin strain-dependent mechanics.

bioRxiv · Jun 15, 2018Biophysics