Increasing the Throughput and Reproducibility of Activity-Based Proteome Profiling Studies with Hyperplexing and Intelligent Data Acquisition
H. G. Budayeva, T. P. Ma, S. Wang, M. Choi, C. M. Rose
The paper introduces InSeqAPI and PairQuant to enhance ABPP throughput and reproducibility using hyperplexing and IDA, identifying new druggable sites in nuclear proteins.
bioRxiv · Sep 13, 2023Biochemistry