RUNX1/RUNX1T1 controls alternative splicing in the t(8;21)-positive acute myeloid leukemia cells
V. Grinev, I. Ilyushonak, R. Clough, S. Nakjang, J. Smink, N. Martinez-Soria, T. Ramanouskaya, C. Bonifer, O. Heidenreich
This study identifies two mechanisms by which RUNX1/RUNX1T1 regulates alternative splicing in t(8;21)-positive acute myeloid leukemia cells, affecting RNA isoform production and protein structure.
bioRxiv · May 4, 2019 · PreprintCancer Biology