Author

R. Clough

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Assay:proteomics· 1

Frequent Co-Authors

A. B. Long· 1 shared A. Lee· 1 shared A. Poddar· 1 shared B. R. Myers· 1 shared C. Bonifer· 1 shared C. D. Arveseth· 1 shared D. J. Nagel· 1 shared F. Nagel· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperCell Biology

A. B. Long

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3 papers

Recent·Most cited

GRK2 Kinases in the Primary Cilium Initiate SMOOTHENED-PKA Signaling in the Hedgehog Cascade

M. F. Walker, J. Zhang, W. Steiner, P.-I. Ku, J.-F. Zhu, Z. Michaelson, Y.-C. Yen, A. Lee, A. B. Long, M. J. Casey, A. Poddar, I. B. Nelson, C. D. Arveseth, F. Nagel, R. Clough, , B. R. Myers

This study identifies GRK2-mediated phosphorylation of SMO in the primary cilium as a critical step initiating SMO-PKA signaling in the Hedgehog pathway.

bioRxiv · May 10, 2023Cell Biology

The Role of the Ovarian Cancer G -Coupled Receptor (OGR1) in Idiopathic Pulmonary Fibrosis

D. J. Nagel, R. Clough, T. J. Bell, W.-Y. Ku, P. Sime, M. Kottmann

This study identifies OGR1 as a negative regulator of fibrotic signaling in IPF, showing reduced OGR1 expression in IPF lung tissue and its role in inhibiting myofibroblast differentiation and TGF-β activation.

bioRxiv · Nov 20, 2019 · PreprintCell Biology

RUNX1/RUNX1T1 controls alternative splicing in the t(8;21)-positive acute myeloid leukemia cells

V. Grinev, I. Ilyushonak, R. Clough, S. Nakjang, J. Smink, N. Martinez-Soria, T. Ramanouskaya, C. Bonifer, O. Heidenreich

This study identifies two mechanisms by which RUNX1/RUNX1T1 regulates alternative splicing in t(8;21)-positive acute myeloid leukemia cells, affecting RNA isoform production and protein structure.

bioRxiv · May 4, 2019 · PreprintCancer Biology