Lkb1 is a master regulator of VSMC fate and function in mice
Z. Cai, P. Song, S. You, Z. Liu, F. Zhao, J. Mu, X. Zheng, Y. Ding, L. Xiao, T. Ramprasath, Y. Qiu, B. He, M.-H. Zou
This study shows that Lkb1 is essential for maintaining vascular smooth muscle cell (VSMC) identity and function in mice, as its deletion leads to vascular abnormalities and aneurysm formation.
bioRxiv · Dec 12, 2020 · PreprintPhysiology