Protection conferred by intraperitoneal Group A Streptococcus immunization relies on macrophages and IFN-γ but not on concurrent adaptive immune responses.
S. Emami, E. Westerlund, T. Rojas Converso, B. Johansson-Lindbom, J. J. Persson
This paper shows that intraperitoneal GAS immunization protects mice through macrophages and IFN-γ, without requiring adaptive immune responses.
bioRxiv · Oct 31, 2023 · PreprintImmunology