CRISPR-Cas12a induced DNA double-strand breaks are repaired by locus-dependent and error-prone pathways in a fungal pathogen
J. Huang, D. Rowe, W. Zhang, T. Suelter, B. Valent, D. Cook
The paper investigates DNA repair mechanisms after CRISPR-Cas12a-induced double-strand breaks in Magnaporthe oryzae, identifying locus-dependent and error-prone repair pathways leading to various mutation types.
bioRxiv · Sep 8, 2021Microbiology