Single extracellular vesicle imaging and computational analysis identifiesinherent architectural heterogeneity
K. S. Kapoor, R. Kalluri, S. Kong, H. Sugimoto, W. Guo, V. Boominathan, Y.-L. Chen, S. L. Biswal, T. Terlier, K. McAndrews
The paper uses cryo-TEM and a segmentation model to analyze EV architecture, finding consistent structural heterogeneity across different sources and purification methods.
bioRxiv · Dec 11, 2023Bioengineering