Implications of the 375W mutation for HIV-1 tropism and vaccine development.
O. Verdejo-Torres, T. Vargas-Pavia, S. Fatima, P. R. Clapham, M. J. Duenas-Decamp
This paper evaluates the effect of the 375W mutation on HIV-1 Env structure and tropism, showing it increases CD4 binding and macrophage tropism across diverse clades.
Journal of Virology · Jan 23, 2024Peer-reviewedMicrobiology