Selective clonal persistence of human retroviruses in vivo: radial chromatin organization, integration site and host transcription
A. Melamed, T. W. Fitzgerald, Y. Wang, J. Ma, E. Birney, C. R. M. Bangham
The paper identifies genomic features that determine the survival of HTLV-1 and HIV-1 clones in vivo, showing that radial chromatin organization, integration site, and host transcription influence clonal persistence.
bioRxiv · Nov 10, 2021Microbiology