An inter-channel cooperative mechanism mediates PIEZO1's exquisite mechanosensitivity
T. Wijerathne, A. D. Ozkan, W. Jiang, Y. Luo, J. J. Lacroix
This study shows that PIEZO1 channels exhibit cooperative behavior under mechanical stress, enhancing their sensitivity to small tension changes through inter-channel interactions.
bioRxiv · Apr 16, 2021 · PreprintBiophysics