Author

Ta-Chun Liu

John Radcliffe Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Assay:fluorescence / live-cell microscopy· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Adam Wollman· 1 shared Akihiro Kusumi· 1 shared Alex Hargreaves· 1 shared Charlotte Fournier· 1 shared Djamila Ouret· 1 shared Isabel Llorente-Garcia· 1 shared Jennifer L. Wilding· 1 shared Jenny Wilding· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperBiophysics

Adam Wollman

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

GMMchi: Gene Expression Clustering Using Gaussian Mixture Modeling

Ta-Chun Liu, Peter N. Kalugin, Jennifer L. Wilding, Walter Fred Bodmer

GMMchi detects bimodal gene expression patterns in cancer data using Gaussian Mixture Modeling and 2x2 contingency tables to analyze genetic and phenotypic correlations.

BMC Bioinformatics · Nov 2, 2022Peer-reviewedBioinformatics

EGF signaling in bowel carcinoma cells utilizes higher order architectures of EGFR and HER2

Adam Wollman, Charlotte Fournier, Isabel Llorente-Garcia, Oliver Harriman, Alex Hargreaves, Sviatlana Shashkova, Peng Zhou, Djamila Ouret, Jenny Wilding, Ta-Chun Liu, Akihiro Kusumi, Walter F Bodmer, Mark C Leake

This study uses single-molecule imaging to show that EGF signaling in carcinoma cells involves EGFR and HER2 clusters with increased stoichiometry after EGF activation.

bioRxiv · Jul 11, 2020 · PreprintBiophysics