Novel Ser74 of NF-kappaB/CgIkappaBalpha Phosphorylated by MAPK/ERK Regulates Temperature Adaptation in Oysters
Chaogang Wang, Zhuxiang Jiang, Mingyang Du, Rihao Cong, Wei Wang, Taiping Zhang, Jincheng Chen, Guofan Zhang, Li Li
The paper identifies a novel phosphorylation site (Ser74) in oyster NF-kappaB/CgI{kappa}B regulated by MAPK/ERK that mediates thermal adaptation through ubiquitin-proteasome degradation and nuclear translocation of CgREL.
bioRxiv · Mar 11, 2024 · PreprintCell Biology