In Vivo Bioincubation Promotes Maturation of Human iPSC-Derived Cardiomyocytes in Neonatal Rat and Pig Hearts
Hanwen Wang, Peter Andersen, Taka Inoue, Narutoshi Hibino, Dong I. Lee, Chulan Kwon
This study shows that in vivo bioincubation of human iPSC-derived cardiomyocytes in neonatal rat and pig hearts promotes maturation to adult-like phenotypes with organized sarcomeres and mature morphology.
bioRxiv · Jul 22, 2026 · PreprintDevelopmental Biology