Author

Takao Yoda

Nagahama Institute of Bio-Science and Technology

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Molecular Biology· 1

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Organism:human· 1 Research Focus:protein design· 1 Assay:protein sequence· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1 Organism:zebrafish· 1

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Hiro TakakuwaiD· 1 shared Tetsuro HiroseiD· 1 shared Tomohiro YamazakiiD· 1 shared

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Hiro TakakuwaORCID

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1 paper

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Molecular BiologyRNAPeer-reviewedJan 22, 2026

Blocky proline/glutamine patterns in the SFPQ intrinsically disordered region dictate paraspeckle formation as a distinct membraneless organelle

Hiro Takakuwa, Takao Yoda, Tomohiro Yamazaki, Tetsuro Hirose

The paper identifies blocky proline/glutamine patterns in the SFPQ IDR as essential for paraspeckle formation and segregation from nuclear speckles through phase separation.

DOI 10.1261/rna.080769.125

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