A truncated form of the p27 CDK inhibitor translated from pre-mRNA causes G2-phase arrest
Daisuke Kaida, Takayuki Satoh, Ken Ishida, Rei Yoshimoto, Kanae Komori
The paper identifies a truncated p27 protein, p27*, that accumulates during G2-phase arrest induced by splicing inhibition and contributes to cell cycle arrest by inhibiting M-phase cyclins.
bioRxiv · Jan 12, 2022 · PreprintMolecular Biology