α/β-Hydrolase domain-containing 6 (ABHD6) accelerates the desensitization and deactivation of TARP γ-2-containing AMPA receptors
Rixu Cong, Huiran Li, Hong Yang, Jing Gu, Shanshan Wang, Qi Liu, Xiangyu Guan, Tangyunfei Su, Yulin Zheng, Dianchun Wang, Xinran Chen, Lei Yang, Yun Stone Shi, Mengping Wei, Chen Zhang
This study shows ABHD6 accelerates AMPAR deactivation and desensitization in the presence of TARP γ-2, with effects dependent on receptor subunit composition and isoforms.
bioRxiv · Jun 20, 2024Neuroscience