Author
Chen Zhang
Capital Medical UniversityORCID 0000-0002-7940-8054Unclaimed ORCID profile · follow to get notified of new preprints
Additional preprints under this name without ORCID
Biology Disciplines
Click to filter author papersSignature Assays, Organisms & Methods
Click to filter · or open tagActivity by Year
2019-2025 · peak 3/yrCo-Author Collaboration Network
10 top collaborators · 5 mutual co-author links9 papers
Recent·Most cited
- Cell BiologybioRxivPreprint
Sialin2 Senses Nitrate to Activate Endosomal PI3K-AKT-NOS Signaling
Xiaoyu Li, Ou Jiang, Zichen Cao…·Songlin Wang
This study identifies Sialin2 as a mammalian nitrate sensor that activates endosomal PI3K-AKT-NOS signaling to enhance angiogenesis and cell survival, offering new therapeutic strategies for vascular disorders.
- NeurosciencebioRxiv
α/β-Hydrolase domain-containing 6 (ABHD6) accelerates the desensitization and deactivation of TARP γ-2-containing AMPA receptors
Rixu Cong, Huiran Li, Hong Yang…·Chen Zhang
This study shows ABHD6 accelerates AMPAR deactivation and desensitization in the presence of TARP γ-2, with effects dependent on receptor subunit composition and isoforms.
DOI 10.7554/elife.99623 - NeuroscienceeLifePeer-reviewed
Establishment of Transgenic Fluorescent Mice for Screening Synaptogenic Adhesion Molecules
Lei Yang, Jingtao Zhang, Sen Liu…·Chen Zhang
This paper develops transgenic mice expressing tdTomato-fused synaptotagmin 1 to label synapses, enabling efficient screening of synaptogenic molecules without immunostaining.
- NeuroscienceComputers in Biology and MedicinePeer-reviewed
FFCM-MRF: An accurate and generalizable cerebrovascular segmentation pipeline for humans and rhesus monkeys based on TOF-MRA
Yue Julia Cui, Haibin Huang, Jialu Liu…·Shan Ping Yu
This paper introduces FFCM-MRF, a cerebrovascular segmentation method for humans and rhesus monkeys, showing improved accuracy and generalizability across datasets and scanners.
- GenomicsBMC BiologyPeer-reviewed
Rapid and sensitive single cell RNA sequencing with SHERRY2
Lin Di, Bo Liu, Yuzhu Lyu…·Yanyi Huang
SHERRY2 is a single-cell RNA sequencing protocol that improves sensitivity and accuracy by eliminating second-strand cDNA synthesis, outperforming existing methods in detecting low-abundance transcripts and specific gene functions.
15 citations - NeurosciencebioRxivPreprint
Cable-free brain imaging with miniature wireless microscopes
Yangzhen Wang, Zhongtian Ma, Wenzhao Li…·Chen Zhang
This paper introduces a wireless mini-microscope (wScope) for real-time brain imaging in freely moving animals, enabling simultaneous recording from up to 8 mice.
- NeurosciencebioRxivPreprint
Deconstruction of the retrosplenial granular cortex for social behavior in the mouse model of fragile X syndrome
Huifang Shang, Ruonan Cai, Hao Sun…·Xiang‐Yao Li
The paper identifies reduced social-related neuronal activity in the retrosplenial granular cortex (RSG) of Fmr1-KO mice, leading to social novelty deficits and suggests RSG manipulation as a potential therapeutic strategy.
6 citations - NeuroscienceNeurobiology of DiseasePeer-reviewed
The critical role of ASD-related gene CNTNAP3 in regulating synaptic development and social behavior in mice
Da-li Tong, Ruiguo Chen, Yulan Lu…·Zilong Qiu
This study identifies CNTNAP3 mutations in ASD cohorts and shows its role in synaptic development and social behavior in mice.
36 citations