Breaking barriers: A new phytomedicine based treatment approach for targeted unrevealed non-canonical DNA structures in tuberculosis bacteria.
Sudipta Bhowmik, Tania Shroff, Sagar Bag, Pratibha Kadam, Nerges Furdoon Mistry
This study investigates how flavonoids interact with non-canonical DNA structures in Mtb, showing they stabilize GQ and iM sequences, potentially enhancing TB drug efficacy.
bioRxiv · Apr 8, 2025 · PreprintBiophysics