CellCage™ Technology Enables High-throughput Isolation of Defined Cell Combinations to Resolve the Determinants of CAR-T mediated Cytotoxicity
Richard G. Yau, Shreya S. Deshmukh, Makenzie Sacca, Ria Gupta, Yanping Yang, Mehdi Mohseni, Liz Y. Wu, Filiz Gorpe Yasar, Shan Sabri, Teresa Ai, Tarun K. Khurana, Shawn Levy, Pier Federico Gherardini, Christopher E. Mason, Moonsoo M. Jin, Gary P. Schroth
The paper introduces CellCage™ technology to isolate defined cell combinations for high-throughput analysis of CAR-T cell cytotoxicity, revealing functional heterogeneity and cooperative behavior in T cell-mediated killing.
bioRxiv · Aug 25, 2026 · PreprintImmunology