BioengineeringbioRxivPreprint
VIP-OT: Dissecting Single-Cell Biochemical State Dynamics under Perturbation via Vibrational Painting and Optimal Transport
Xuemeng Li, Stefan G. Stark, Xinwen Liu…·Jian Shu
VIP-OT traces drug response heterogeneity in single cells using vibrational imaging and optimal transport to predict post-treatment metabolic states from pre-treatment spectra.