Transcriptome profiles in brains of mice heterozygous for a DYT1 dystonia-associated mutation in the endogenous Tor1a gene
Sara B. Mitchell, Michael S. Chimenti, Hiroyuki Kawano, Tsun Ming Tom Yuen, Ashley E. Sjurson, Sadahiro Iwabuchi, Kevin Lee Knudtson, Thomas Bair, Diana L. Kolbe, Nobutoshi C. Harata
The paper examines transcriptome profiles in mouse brain regions with a DYT1 dystonia mutation, finding subtle genotype-dependent changes across regions but not within individual regions.
bioRxiv · Oct 31, 2019 · PreprintNeuroscience