Author

Thomas Dowe

King's College Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Adam ShlieniD· 1 shared Andrew R. J. LawsoniD· 1 shared Angus HodderiD· 1 shared Anil Kumar DhawaniD· 1 shared Anna WengeriD· 1 shared Charlotte Town· 1 shared Claire TrayersiD· 1 shared Conor ParksiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Adam ShlienORCID

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1 paper

Recent·Most cited

Extensive and differential platinum chemotherapy mutagenesis in children

Anna Wenger, Henry Lee-Six, Manàs Dave, Mehdi Layeghifard, Andrew R. J. Lawson, Federico Abascal, Pantelis A. Nicola, Taryn D. Treger, Toochi Ogbonnah, Conor Parks, Thomas R. W. Oliver, Jonathan Kennedy, Angus Hodder, Nathaniel D. Anderson, Felipe Luz Torres Silva, , Sam Behjati

This study uses duplex sequencing to analyze platinum chemotherapy-induced mutagenesis in pediatric tissues, revealing extensive mutational signatures and tissue-specific effects.

bioRxiv · Oct 12, 2025 · PreprintCancer Biology