Author

Thomas Duffield

University of Liverpool

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:database / resource· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

João Pedro de MagalhãesiD· 2 shared Arda Akalan· 1 shared Cyril LaggeriD· 1 shared Daniel H. PalmeriD· 1 shared Gustavo Daniel Vega Magdaleno· 1 shared Laura CsukaiD· 1 shared Ludovic Senez· 1 shared Marian BreueriD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBioinformatics

João Pedro de MagalhãesORCID

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2 papers

Recent·Most cited

Mosaic Regulation of Stress Pathways Underlies Senescent Cell Heterogeneity

Roberto A. Avelar, Thomas Duffield, Cyril Lagger, Nikita Krstevska, Marian Breuer, João Pedro de Magalhães

The paper identifies senescent cell heterogeneity by analyzing stress response enrichment in bulk RNA-seq data and proposes a model based on Stress Response Modules.

bioRxiv · Oct 3, 2024 · PreprintBioinformatics

Epigenetic fidelity in complex biological systems and implications for ageing

Thomas Duffield, Laura Csuka, Arda Akalan, Gustavo Daniel Vega Magdaleno, Ludovic Senez, Daniel H. Palmer, João Pedro de Magalhães

This paper identifies epigenetic loci with age-correlated variance, introduces a deep-learning model to predict age from variance, and proposes a theory of systemic ageing through feedback deregulation.

bioRxiv · Apr 29, 2023 · PreprintGenomics