Dynamic landscape of protein occupancy across the Escherichia coli chromosome
Peter L. Freddolino, Haley M. Amemiya, Thomas J. Goss, Saeed Tavazoie
The paper uses IPOD-HR to globally map protein-DNA interactions in E. coli, revealing dynamic transcription factor occupancy and stable nucleoid factor domains, and develops computational models for transcription factor specificity.
PLoS Biology · Jun 25, 2021Peer-reviewedSystems Biology