Author

Thorsten R. Klingen

Helmholtz Centre for Infection Research

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Research Focus:variant calling· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Alice Carolyn McHardyiD· 2 shared Gülşah GabrieliD· 2 shared Jens Uwe LoersiD· 2 shared Frank KlawonniD· 1 shared Kyra MooreniD· 1 shared Stephanie Stanelle‐BertramiD· 1 shared Susanne ReimeringiD· 1 shared Thomas KreyiD· 1 shared

Activity by Year

2018-2019 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 24 mutual co-author links

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2 shared papersBioinformatics

Alice Carolyn McHardyORCID

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2 papers

Recent·Most cited

Structures and functions linked to genome-wide adaptation of human influenza A viruses

Thorsten R. Klingen, Jens Uwe Loers, Stephanie Stanelle‐Bertram, Gülşah Gabriel, Alice Carolyn McHardy

The paper compares genome-wide adaptation of H3N2 and pH1N1 influenza A viruses, identifying regions under positive selection and linking them to host adaptation and drug resistance.

Scientific Reports · Apr 18, 2019Peer-reviewedBioinformatics

Sweep Dynamics (SD) plots: Computational identification of selective sweeps to monitor the adaptation of influenza A viruses

Thorsten R. Klingen, Susanne Reimering, Jens Uwe Loers, Kyra Mooren, Frank Klawonn, Thomas Krey, Gülşah Gabriel, Alice Carolyn McHardy

The paper introduces SD plots to identify selective sweeps in influenza A virus genomes, showing their use in tracking adaptive changes in pH1N1 and sH3N2 viruses.

Scientific Reports · Jan 4, 2018Peer-reviewedBioinformatics