Frank Klawonn

This study compares T cell development in humanized mice with and without murine MHC, finding that busulfan conditioning in MHC-deficient mice promotes activated T cells while irradiation favors naive T cells.

This study develops next-generation CD30CAR-T cells using CRISPR/Cas9 for multiplex editing, showing high potency but risks of translocations with combined knockouts.

CoVerage predicts and characterizes SARS-CoV-2 Variants of Interest by analyzing lineage frequency dynamics and antigenic changes from GISAID data.

This study shows human T-cell development in humanized mice can occur without mouse MHCs and is enhanced by lentiviral delivery of HLA and cytokines.

Haploflow assembles viral strain genomes from mixed samples, outperforming existing assemblers in speed and accuracy on benchmark datasets.

This study evaluates the replicability, repeatability, and long-term reproducibility of three cerebellar morphometry tools using MRI data from different studies.

The paper introduces SD plots to identify selective sweeps in influenza A virus genomes, showing their use in tracking adaptive changes in pH1N1 and sH3N2 viruses.