Thomas Krey

A dual role in virion attachment and entry makes the human cytomegalovirus gHgLgO trimer the central player in virion infectivity

The paper identifies gHgLgO as the central player in HCMV infectivity by showing its role in HSPG binding and infectivity, challenging previous views on gB and gMgN complexes.

Computationally designed stem-epitope mimetics elicit broadly reactive antibodies

This study designs stem-epitope mimetics using computational methods to elicit broadly reactive antibodies against influenza viruses.

Rosetta FunFolDes - a general framework for the computational design of functional proteins

This paper introduces a computational framework for designing functional proteins by integrating folding and sequence design, showing that functional motifs can be embedded without requiring the global energy minimum.

Sweep Dynamics (SD) plots: Computational identification of selective sweeps to monitor the adaptation of influenza A viruses

The paper introduces SD plots to identify selective sweeps in influenza A virus genomes, showing their use in tracking adaptive changes in pH1N1 and sH3N2 viruses.