Author

Tianrui Lyu

Chinese University of Hong Kong

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Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 1 Approach:experimental assay· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Fei TengiD· 1 shared Goran StjepanovićiD· 1 shared Ming Liu· 1 shared Ming-Yuan SuiD· 1 shared Shan WangiD· 1 shared Xi Wang· 1 shared Xinyi MaiiD· 1 shared Yang WangiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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8 top collaborators · 28 mutual co-author links

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1 shared paperBiochemistry

Fei TengORCID

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1 paper

Recent·Most cited

Mechanism of D-type cyclins recognition by the AMBRA1 E3 ligase receptor

Yang Wang, Ming Liu, Shan Wang, Xinyi Mai, Xi Wang, Fei Teng, Tianrui Lyu, Ming-Yuan Su, Goran Stjepanović

The paper determines the cryo-EM structure of the AMBRA1-DDB1 complex bound to cyclin D1, revealing the molecular mechanism of cyclin D1 recognition and its regulation by phosphorylation.

Science Advances · May 23, 2025Peer-reviewedBiochemistry