Inhibition mechanism of pancreatic KATP channels by centipede toxins
Tianyi Hou, Mengmeng Wang, Yongmei Tan, Chengpeng Fan, Lei Chen
This paper identifies centipede toxins SpTx1 and Sm3a as inhibitors of human pancreatic KATP channels, revealing their binding mechanism and therapeutic potential for neonatal diabetes.
Research · Jan 1, 2026Peer-reviewedBiophysics