Drugging the Medullary Thyroid Cancer Surfaceome with T Cell Engagers Targeting CEA, GFRA4 and DLL3 as Monotherapy and In Combination with Tyrosine Kinase Inhibitors
This paper identifies CEA, DLL3, and GFRA4 as potential targets for T cell engagers in medullary thyroid cancer and shows their efficacy as monotherapy and in combination with tyrosine kinase inhibitors.
bioRxiv · Aug 5, 2025 · PreprintImmunology