Determining cell fate specification and genetic contribution to cardiac disease risk in hiPSC-derived cardiomyocytes at single cell resolution
Quan Hoang Nguyen, Samuel W. Lukowski, Han Sheng Chiu, Clayton E. Friedman, Anne Senabouth, Liam Crowhurst, Timothy J.C Bruxmer, Angelika N. Christ, Nathan J. Palpant, Joseph E. Powell
The paper reconstructs cell fate trajectories in hiPSC-derived cardiomyocytes using single-cell RNA-seq and identifies genes with dynamic roles in cardiovascular disease risk.
bioRxiv · Dec 5, 2017 · PreprintGenomics