Author

Angelika N. Christ

The University of QueenslandORCID 0000-0002-8680-2367Unclaimed ORCID profile · follow to get notified of new preprints

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Research Focus:differential expression· 3 Organism:human· 3 Research Focus:clustering· 2 Research Focus:gene regulatory network inference· 2 Approach:machine learning (classical)· 2 Assay:scRNA-seq· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Anne SenabouthiD· 3 shared Han Sheng ChiuiD· 3 shared Joseph E. PowelliD· 3 shared Nathan J. PalpantiD· 3 shared Quan Hoang NguyeniD· 3 shared Samuel W. LukowskiiD· 3 shared Clayton E. FriedmaniD· 2 shared Timothy J. C. BruxneriD· 2 shared

Activity by Year

2017-2018 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersGenomics

Anne SenabouthORCID

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3 papers

Recent·Most cited

Single-Cell Transcriptome Sequencing Of Human Induced Pluripotent Stem Cells Identifies Differentially Primed Subpopulations

Quan Hoang Nguyen, Samuel W. Lukowski, Han Sheng Chiu, Anne Senabouth, Timothy J. C. Bruxner, Angelika N. Christ, Nathan J. Palpant, Joseph E. Powell

The paper identifies four transcriptionally distinct subpopulations in human induced pluripotent stem cells using single-cell RNA sequencing and develops a machine learning method to classify and predict transitions between these states.

Genome Research · Jul 1, 2018Peer-reviewedGenomics

Cardiac differentiation at single cell resolution reveals a requirement of hypertrophic signaling for HOPX transcription

Clayton E. Friedman, Quan Hoang Nguyen, Samuel W. Lukowski, Han Sheng Chiu, Abbigail Helfer, Jason Wayne Miklas, Shengbao Suo, Jing‐Dong J. Han, Pierre Osteil, Guangdun Peng, Naihe Jing, Gregory J. Baillie, Anne Senabouth, Angelika N. Christ, Timothy J. C. Bruxner, , Nathan J. Palpant

The paper maps cardiac differentiation at single-cell resolution, identifies HOPX dysregulation, and shows hypertrophic signaling is required for HOPX transcription in hPSC-derived cardiomyocytes.

bioRxiv · Jun 20, 2018 · PreprintDevelopmental Biology

Determining cell fate specification and genetic contribution to cardiac disease risk in hiPSC-derived cardiomyocytes at single cell resolution

Quan Hoang Nguyen, Samuel W. Lukowski, Han Sheng Chiu, Clayton E. Friedman, Anne Senabouth, Liam Crowhurst, Timothy J.C Bruxmer, Angelika N. Christ, Nathan J. Palpant, Joseph E. Powell

The paper reconstructs cell fate trajectories in hiPSC-derived cardiomyocytes using single-cell RNA-seq and identifies genes with dynamic roles in cardiovascular disease risk.

bioRxiv · Dec 5, 2017 · PreprintGenomics