A synthetic biology approach to bacterial transcription initiation: RNA aptamer based in vitro transcription assay for rapidly testing bacterial RNA polymerases, promoters and inhibitors.
Tina Lanzmaier, Elena Madeleine Reiterer, Melanie Merl, Andonita Ajdari, Karin Bischof, Günther Koraimann
The paper introduces an in vitro transcription assay using a Broccoli RNA aptamer to test bacterial RNA polymerases, promoters, and inhibitors, showing its utility for drug discovery.
bioRxiv · Aug 12, 2026 · PreprintSynthetic Biology