Cross-species analysis of experimental PH at single cell resolution reveals prominent contributions Ednrb+ EC and Dhcr24+ macrophage populations
Bolun Li, Yanjiang Xing, Yitian Zhou, Xingqi Xiao, Ting Shu, Xiaomin Song, Hongmei Zhao, Xiao-Jian Wang, Junling Pang, Peiran B Yang, Paul B. Yu, Jing Wang, Wang Chen
The paper integrates cross-species single-cell data from rodent PH models and human disease to identify overlapping cell subsets and novel macrophage and endothelial subtypes involved in PH.
bioRxiv · Apr 30, 2025 · PreprintBioinformatics