Cell segmentation-free inference of cell types from in situ transcriptomics data
Jeongbin Park, Wonyl Choi, Sebastian Tiesmeyer, Brian Long, Lars E. Borm, Emma J. Garren, Thuc Nghi Nguyen, Bosiljka Tasic, Simone Codeluppi, Tobias Graf, Matthias Schlesner, Oliver Stegle, Roland Eils, Naveed Ishaque
This paper introduces SSAM, a cell segmentation-free method for cell-type identification and tissue domain detection in in situ transcriptomics data, showing it detects known and discovers new cell types in mouse brain tissues.
Nature Communications · Jun 10, 2021Peer-reviewedBioinformatics