Simone Codeluppi

This paper introduces EEL FISH, a method for spatial transcriptome profiling that improves throughput while maintaining single-cell resolution, applied to mouse and human tissues.

This paper introduces SSAM, a cell segmentation-free method for cell-type identification and tissue domain detection in in situ transcriptomics data, showing it detects known and discovers new cell types in mouse brain tissues.

The paper introduces an imaging-free spatial transcriptomics technique called STRP-seq, validated on murine and lizard brains, revealing regional molecular anatomy.

The paper maps cell types in the mouse nervous system using single-cell RNA sequencing and identifies distinct astrocyte and oligodendrocyte subtypes with specific molecular and spatial characteristics.

The paper uses single-cell transcriptomics to show that embryonic Pdgfra+ cells give rise to OPCs with convergent transcriptional profiles in different CNS regions.

The paper develops a cyclic smFISH method to map cell-specific markers in the somatosensory cortex, revealing its spatial organization using markers from single-cell transcriptomics.