Endogenous Real Time Imaging Reveals Dynamic Chromosomal Mobility During Ligand-Mediated Transcriptional Burst Events
Susan Siyu Wang, Thomas Suter, Amir Gamliel, Yeeun Kim, Sreejith J. Nair, Soohwan Oh, Feng Yang, Kenneth A. Ohgi, Tobias Wagner, Steven Gan, Michael G. Rosenfeld
The paper uses live cell imaging to study chromosomal dynamics during estrogen receptor-mediated transcriptional bursts and non-burst phases, revealing changes in locus mobility and condensate formation.
bioRxiv · Aug 18, 2025 · PreprintMolecular Biology