Small-molecule IGF1R inhibitors extend healthspan in a mouse model
Yulia Balandina, Tom Stadnikov, Gregory S. Basarab, Charles J. Eyermann, Alexander Suvorov
This study tests small-molecule IGF1R inhibitors in mice to extend healthspan, finding improved physiological parameters and extended healthspan in one compound, but with toxicity and side effects.
bioRxiv · Apr 15, 2026 · PreprintDevelopmental Biology