Analysis-ready VCF at Biobank scale using Zarr
Eric Czech, Will Tyler, Tom White, Ben Jeffery, Timothy R. Millar, Benjamin Elsworth, Jérémy Guez, Jonny Hancox, Konrad J. Karczewski, Alistair Miles, Sam Tallman, Per Unneberg, Rafal Wojdyla, Shadi Zabad, Jeff Hammerbacher, Jerome Kelleher
The paper introduces VCF Zarr, a format for efficiently storing and processing large-scale genetic variation data, demonstrating improved performance and scalability over traditional VCF formats.
GigaScience · Jan 1, 2025Peer-reviewedBioinformatics