Alistair Miles

The paper provides genomic resources for malaria vector surveillance in Southeast Asia, revealing population structure and resistance regions in Anopheles dirus.

This study uses whole-genome sequencing to analyze genomic connectivity and adaptive gene flow of insecticide resistance alleles in Anopheles arabiensis across East Africa, revealing transboundary spread despite geographic barriers.

The paper identifies genomic signatures of selection in Anopheles funestus across African populations, revealing shared and population-specific adaptive variation linked to insecticide resistance and neuromodulatory pathways.

This study uses genomic data to analyze evolutionary dynamics of Anopheles gambiae under different insecticidal tools, revealing distinct resistance mechanisms and allele frequency shifts.

The paper analyzes genomic diversity in Anopheles funestus across Africa, identifying genetic variation, adaptation signals, and conservation of a gene drive target.

The paper identifies and characterizes genomic regions under positive selection in malaria vectors using whole-genome sequencing data from 4,306 mosquitoes across twenty-one countries.

This paper uses genomic surveillance in a cluster randomized trial to detect insecticide resistance variants in Ugandan Anopheles funestus and An. gambiae s.l., showing differential population responses to pyrethroid and PBO interventions.

This study uses whole-genome sequencing of Anopheles gambiae s.l. mosquitoes to uncover fine-scale population structure and insecticide resistance mechanisms in central Ghana.

This paper develops a targeted genomic surveillance approach for insecticide resistance in malaria vectors, identifying resistance variants and demonstrating predictive modeling with high accuracy.

The paper analyzes the population genetics of Anopheles funestus in Tanzania, identifying two distinct genetic populations with different resistance backgrounds and suggesting geographic barriers to gene flow.

The paper introduces VCF Zarr, a format for efficiently storing and processing large-scale genetic variation data, demonstrating improved performance and scalability over traditional VCF formats.

The paper investigates insecticide resistance and population structure in Anopheles gambiae from southern DRC, finding high resistance and genetic differentiation between populations.

The paper identifies cis-regulated genes and cis-regulatory modules in Anopheles gambiae associated with insecticide resistance using allele-specific expression and machine learning.

This study examines migration patterns among malaria vector species using genomic data, finding variation in genetic differentiation and migration rates across regions and species.

The paper discovers knock-down resistance (kdr) mutations in Anopheles funestus, a major malaria vector, showing resistance to DDT but not deltamethrin.

This study identifies copy number variants (CNVs) as key drivers of insecticide resistance in Anopheles arabiensis, revealing new gene clusters and resistance mechanisms to deltamethrin and pirimiphos-methyl.

This study identifies a duplicated esterase locus associated with pirimiphos-methyl resistance in Anopheles gambiae through population genomic analysis.

This study identifies novel genetic loci associated with resistance to pyrethroid and organophosphate insecticides in Anopheles gambiae s.l. through genome-wide association analyses.

AgamPrimer designs primers and probes for Anopheles gambiae using genomic variation data to avoid amplification issues caused by genetic diversity.

The paper develops a molecular barcode and online tool to identify and map imported Plasmodium vivax infections using SNP analysis and machine learning.

The paper uses whole-genome sequencing to analyze genetic diversity and population structure of An. minimus in Cambodia, identifying four distinct populations with unique selection signals.

The paper examines genetic variation in the Cyp6m2 gene across Anopheles mosquito populations and finds no evidence of directional selection on missense variants linked to insecticide resistance.

This study identifies novel genetic variants and haplotypes associated with pyrethroid resistance in malaria vectors, revealing complex resistance mechanisms and geographical spread.

The paper identifies a resistance mechanism to pirimiphos-methyl in Anopheles mosquitoes through duplication and introgression of the Ace1 locus, showing its spread in West Africa.

The paper analyzes genome variation in 1,142 Anopheles mosquitoes to study population structure and insecticide resistance.

The paper sequences genomes of 765 malaria vector mosquitoes to study genetic diversity and insecticide resistance.

The paper uses deep sequencing of genetic crosses in Plasmodium falciparum to analyze genome variation and meiotic recombination, revealing INDELs as dominant polymorphisms and providing insights into recombination patterns and drug resistance mechanisms.

This study identifies kelch13 mutations associated with artemisinin resistance in Southeast Asia and finds low frequency of these mutations in Africa, suggesting different evolutionary pressures.