5-Deazaflavin (TND1128) and its hybrid analogs are cytoprotective against hydrogen peroxide (H2O2)-induced oxidative stress.
Kaori Kubota, Shutaro Katsurabayashi, Takuya Watanabe, Katsunori Iwasaki, Tomohisa Nagamatsu, Norio Akaike
This study shows that TND1128 and its analogs protect cells from H2O2-induced oxidative stress by enhancing mitochondrial function.
bioRxiv · May 7, 2024 · PreprintPharmacology & Toxicology