Absence of nascent peptides triggers nonfunctional ribosome decay
Tomoko Sakata, Kotaro Fujii, Makoto Kitabatake
The paper shows that Reh1 detects defective ribosomes by sensing the absence of nascent peptides, leading to ubiquitination of Rpl19 and triggering nonfunctional ribosome decay.
bioRxiv · May 21, 2026 · PreprintMolecular Biology