Cryo-EM structures of human zinc transporter ZnT7 reveal the mechanism of Zn2+ uptake into the Golgi apparatus
Han Ba Bui, Satoshi P. Watanabe, Norimichi Nomura, Kehong Liu, Tomoko Uemura, Michio Inoue, Akihisa Tsutsumi, Hiroyuki Fujita, Kengo Kinoshita, So Iwata, Masahide Kikkawa, Kenji Inaba
The paper presents cryo-EM structures of human ZnT7, revealing its mechanism for Zn2+ uptake into the Golgi apparatus through conformational changes and histidine-rich loop interactions.
bioRxiv · Mar 23, 2022 · PreprintMolecular Biology