Quantitative super-resolution imaging with deep learning segmentation reveals early mitochondrial network remodeling and altered mitochondria-lysosome interactions in Pompe disease muscle
Ibrahim Hassani, Johan Deniaud, Chantal Thorin, Tony Fiore, Laurence Dubreil, Karl Rouger, Marie-Anne Colle
This study uses super-resolution imaging and deep learning to quantify mitochondrial and lysosomal changes in Pompe disease mice, revealing early mitochondrial remodeling and altered mitochondria-lysosome interactions.
bioRxiv · Sep 11, 2026 · PreprintPathology