Laurence Dubreil

This study uses super-resolution imaging and deep learning to quantify mitochondrial and lysosomal changes in Pompe disease mice, revealing early mitochondrial remodeling and altered mitochondria-lysosome interactions.

This study shows that Seipin regulates tripartite ER-mitochondria-lipid droplet contact sites, which are critical for adipocyte lipid storage and metabolic flexibility.

This paper identifies miR-187 as a regulator of early oogenesis and female fecundity in medaka through CRISPR/Cas9 knockout and transcriptomic analysis.

This paper develops a three-step bioprocess using stirred tank bioreactors to produce extracellular vesicles from pancreatic beta cells, enhancing their maturation and immunomodulatory properties.