PathologybioRxivPreprint
Quantitative super-resolution imaging with deep learning segmentation reveals early mitochondrial network remodeling and altered mitochondria-lysosome interactions in Pompe disease muscle
Ibrahim Hassani, Johan Deniaud, Chantal Thorin…·Marie-Anne Colle
This study uses super-resolution imaging and deep learning to quantify mitochondrial and lysosomal changes in Pompe disease mice, revealing early mitochondrial remodeling and altered mitochondria-lysosome interactions.