Groove architecture controls lipid scrambling in simulations of protein and model systems
Harper E. Smith, Travis Harrison-Rawn, Wang Zheng, Ángela Ballesteros, Marcos M. Sotomayor
This study uses simulations to show that groove architecture, not amino acid sequence, determines lipid scrambling in scramblase proteins.
bioRxiv · Jun 27, 2025 · PreprintBiophysics