Whole blood transcriptional responses associated with bacterial burden in pulmonary tuberculosis
Le Thanh Hoang Nhat, Triet Minh Thai, Hoang Thanh Hai, Le Hong Van, Le Nguyen Hong Thai, Trinh Thi Bich Tram, Do Dang Anh Thu, Thi Minh Ha Dang, Nghia Ho Dang Trung, Guy Edward Thwaites, Nguyễn Thụy Thương Thương
This study identifies a 1,093-gene module associated with Mtb burden in PTB, driven by neutrophils and monocytes, and highlights CNIH4 as a key predictor of bacterial burden.
bioRxiv · Jan 29, 2026 · PreprintImmunology